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Tdark
MMTAG2
Multiple myeloma tumor-associated protein 2

Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.14   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 59   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.14   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 59   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
adolescent idiopathic scoliosis
2
1
0
1.2
46.1
birth weight
1
1
1
33.1
diastolic blood pressure
1
1
1
21.5
Agents acting on the renin-angiotensin system use measurement
1
1
1
9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
adolescent idiopathic scoliosis
0
1.2
46.1
birth weight
1
33.1
diastolic blood pressure
1
21.5
Agents acting on the renin-angiotensin system use measurement
1
9
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BU76-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Immune System (R-HSA-168256)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Immune System
Reactome
Innate Immune System
Reactome
Neutrophil degranulation
Name
Explore in Pharos
Explore in Source
Immune System
Innate Immune System
Neutrophil degranulation
Gene Ontology Terms (5)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (27)
1 – 10 of 27
RBM34
Tdark
Novelty:  0.58131282
Score:  0.843
Data Source:  STRINGDB
RBMX2
Tbio
Novelty:  0.08867468
Score:  0.808
Data Source:  STRINGDB
PRKRA
Tbio
Family:  Kinase
Novelty:  0.02115618
Score:  0.742
Data Source:  STRINGDB
TARBP2
Tbio
Novelty:  0.01485994
Score:  0.742
Data Source:  STRINGDB
PRPF19
Tbio
Novelty:  0.01616737
Score:  0.736
Data Source:  STRINGDB
SLC2A13
Tbio
Family:  Transporter
Novelty:  0.04641021
Score:  0.731
Data Source:  STRINGDB
FAM133A
Tbio
Novelty:  0.09902536
Score:  0.689
Data Source:  STRINGDB
MRPL55
Tdark
Novelty:  0.55956177
Score:  0.673
Data Source:  STRINGDB
SCARA5
Tbio
Novelty:  0.01727557
Score:  0.651
Data Source:  STRINGDB
GUK1
Tbio
Family:  Kinase
Novelty:  0.00475753
Score:  0.648
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.14

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer