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Tbio
CHCHD5
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000324913
  • ENSP00000325655
  • ENSG00000125611
  • ENST00000409719
  • ENSP00000386994

Symbol
  • C2orf9
  • CHTM1
  • MIC14
  • MIX14
  • C2orf9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.94
histone modification site profile
0.92
transcription factor binding site profile
0.9
tissue sample
0.7
virus perturbation
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.44   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 156   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.44   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 156   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
FUCA1
Tchem
Family:  Enzyme
Novelty:  0.00961721
p_int:  0.999996983
p_ni:  0.000001896
p_wrong:  0.000001121
Score:  0.517
Data Source:  BioPlex,STRINGDB
CHCHD4
Tbio
Novelty:  0.01204944
p_int:  0.999978993
p_ni:  0.000017163
p_wrong:  0.000003844
Score:  0.955
Data Source:  BioPlex,STRINGDB
HCCS
Tbio
Family:  Enzyme
Novelty:  0.0022585
p_int:  0.999905783
p_ni:  0.000094217
Data Source:  BioPlex
SUOX
Tbio
Family:  Enzyme
Novelty:  0.00971136
p_int:  0.998423675
p_ni:  0.00157602
p_wrong:  3.05e-7
Data Source:  BioPlex
KPRP
Tdark
Novelty:  0.11744927
p_int:  0.986858216
p_ni:  0.013141784
Data Source:  BioPlex
CDSN
Tbio
Novelty:  0.01118491
p_int:  0.943525082
p_ni:  0.0564677
p_wrong:  0.000007219
Data Source:  BioPlex
KLK7
Tchem
Family:  Enzyme
Novelty:  0.00757766
p_int:  0.891731062
p_ni:  0.057481499
p_wrong:  0.050787439
Data Source:  BioPlex
TTC19
Tbio
Novelty:  0.08251578
p_int:  0.849462477
p_ni:  0.15053752
p_wrong:  3e-9
Data Source:  BioPlex
GFER
Tchem
Family:  Enzyme
Novelty:  0.00338563
p_int:  0.774611424
p_ni:  0.171937021
p_wrong:  0.053451555
Score:  0.921
Data Source:  BioPlex,STRINGDB
CYC1
Tchem
Novelty:  0.01369865
Score:  0.907
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (2)
Mitochondrial protein import (R-HSA-1268020)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Mitochondrial protein import
Reactome
Protein localization
Name
Explore in Pharos
Explore in Source
Mitochondrial protein import
Protein localization
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking status measurement
1
1
1
21.5
smoking behavior
1
1
1
17.8
C-reactive protein measurement
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking status measurement
1
21.5
smoking behavior
1
17.8
C-reactive protein measurement
1
15.8
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil-helix-coiled-coil-helix domain containing 5
VGNC:194
459496
Macaque
coiled-coil-helix-coiled-coil-helix domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17840]
Mouse
MGI:1913420
66170
Rat
RGD:1307809
296147
Dog
coiled-coil-helix-coiled-coil-helix domain containing 5
VGNC:39197
611820
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil-helix-coiled-coil-helix domain containing 5
Macaque
coiled-coil-helix-coiled-coil-helix domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17840]
Mouse
Rat
Dog
coiled-coil-helix-coiled-coil-helix domain containing 5
Publication Statistics
PubMed Score 7.44
PubMed score by year
PubTator Score 5.03
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title