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Tbio
SYT17
Synaptotagmin-17

Protein Summary
Description
Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355377
  • ENSP00000347538
  • ENSG00000103528

Symbol
  • sytXVII
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.77
trait
0.61
transcription factor perturbation
0.61
phenotype
0.59
PubMedID
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.94   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 129   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.94   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 129   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (66)
TF
Tbio
Novelty:  0.00231826
p_int:  0.953220076
p_ni:  0.046779924
Score:  0.219
Data Source:  BioPlex,STRINGDB
MID2
Tbio
Family:  Enzyme
Novelty:  0.01349913
p_int:  0.789103121
p_ni:  0.000146341
p_wrong:  0.210750538
Score:  0.557
Data Source:  BioPlex,STRINGDB
SNAP25
Tclin
Novelty:  0.00148905
Score:  0.774
Data Source:  STRINGDB
STX3
Tbio
Novelty:  0.01055819
Score:  0.703
Data Source:  STRINGDB
UNC13B
Tbio
Novelty:  0.00429808
Score:  0.671
Data Source:  STRINGDB
VAMP2
Tbio
Novelty:  0.00187736
Score:  0.671
Data Source:  STRINGDB
SNAP23
Tbio
Novelty:  0.0065371
Score:  0.67
Data Source:  STRINGDB
STX1A
Tbio
Novelty:  0.00087207
Score:  0.645
Data Source:  STRINGDB
CPLX1
Tbio
Novelty:  0.01434543
Score:  0.637
Data Source:  STRINGDB
NCF2
Tbio
Novelty:  0.00274685
Score:  0.628
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (18)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
49.5
2
1
0
1.1
45.2
diet measurement
1
1
1
31.4
maximum cigarettes per day measurement
1
1
0
6
4.6
diastolic blood pressure
1
1
1
4.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
49.5
0
1.1
45.2
diet measurement
1
31.4
maximum cigarettes per day measurement
0
6
4.6
diastolic blood pressure
1
4.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
synaptotagmin 17
694130
Mouse
MGI:104966
110058
Rat
RGD:708576
192189
Dog
synaptotagmin 17
479829
Horse
synaptotagmin 17
VGNC:23820
100052854
Species
Name
OMA
EggNOG
Inparanoid
Macaque
synaptotagmin 17
Mouse
Rat
Dog
synaptotagmin 17
Horse
synaptotagmin 17
Publication Statistics
PubMed Score 19.94
PubMed score by year
PubTator Score 0.34
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title