Tbio FEM1A Protein fem-1 homolog A

Protein Summary

Description

Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit (By similarity). May participate in antiinflammatory signaling via its interaction with PTGER4.

Uniprot Accession IDs

• Q9BSK4
• B2RDI3
• Q711P8
• Q9NPN7
• Q9NPW8
• FEM1a

Gene Name

• FEM1A

Ensembl ID

• ENST00000269856
• ENSP00000269856
• ENSG00000141965

Symbol

• EPRAP
• EPRAP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.95
histone modification site profile	0.72
disease perturbation	0.68
tissue sample	0.62
small molecule perturbation	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.32   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 138   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.32   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 138   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0