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Tbio
TUBGCP2
Gamma-tubulin complex component 2

Protein Summary
Description
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000252936
  • ENSP00000252936
  • ENSG00000130640
  • ENST00000368563
  • ENSP00000357551
  • ENST00000417178
  • ENSP00000395666
  • ENST00000543663
  • ENSP00000446093

Symbol
  • GCP2
  • ALP4
  • GCP2
  • GCP-2
  • SPC97
  • h103p
  • hGCP2
  • SPBC97
  • Spc97p
  • hSpc97
  • Grip103
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.97
disease perturbation
0.74
cell type or tissue
0.71
kinase perturbation
0.71
cellular component
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 57.85   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 154   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 57.85   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 154   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (208)
MZT2B
Tdark
Novelty:  0.69469786
p_int:  0.999978806
p_ni:  0.000021194
Score:  0.995
Data Source:  BioPlex,STRINGDB
TUBGCP5
Tbio
Novelty:  0.04863776
p_int:  0.999852587
p_ni:  0.000147413
Score:  0.992
Data Source:  BioPlex,STRINGDB
MZT1
Tdark
Novelty:  0.06713659
p_int:  0.999436514
p_ni:  0.000563486
Score:  0.997
Data Source:  BioPlex,STRINGDB
TXNDC12
Tbio
Novelty:  0.01354011
p_int:  0.998394955
p_ni:  0.001605045
Score:  0.774
Data Source:  BioPlex,STRINGDB
TUBG2
Tbio
Novelty:  0.14828466
p_int:  0.997566344
p_ni:  0.002433656
Score:  0.996
Data Source:  BioPlex,Reactome,STRINGDB
OPRM1
Tclin
Family:  GPCR
Novelty:  0.0003701
p_int:  0.994884016
p_ni:  0.005115984
Data Source:  BioPlex
C5AR2
Tbio
Family:  GPCR
Novelty:  0.01193736
p_int:  0.969612347
p_ni:  0.030387653
Data Source:  BioPlex
LGALS3BP
Tbio
Novelty:  0.0025302
p_int:  0.969590499
p_ni:  0.030409501
Score:  0.532
Data Source:  BioPlex,STRINGDB
NPY2R
Tchem
Family:  GPCR
Novelty:  0.01177255
p_int:  0.964135703
p_ni:  0.035864297
Data Source:  BioPlex
MAS1
Tchem
Family:  GPCR
Novelty:  0.0089712
p_int:  0.939539629
p_ni:  0.060460371
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (9)
Cell Cycle (R-HSA-1640170)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 9
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cell Cycle
Reactome
Cell Cycle, Mitotic
Reactome
Centrosome maturation
Reactome
G2/M Transition
Reactome
M Phase
Name
Explore in Pharos
Explore in Source
Cell Cycle
Cell Cycle, Mitotic
Centrosome maturation
G2/M Transition
M Phase
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urinary metabolite measurement
1
1
1
67.3
blood metabolite measurement
1
1
1
57.8
longevity
1
1
0
3.5
40.7
testosterone measurement
1
1
1
28.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urinary metabolite measurement
1
67.3
blood metabolite measurement
1
57.8
longevity
0
3.5
40.7
testosterone measurement
1
28.1
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tubulin gamma complex associated protein 2
VGNC:7271
450849
Macaque
tubulin gamma complex associated protein 2
702201
Mouse
MGI:1921487
74237
Rat
RGD:1309597
309098
Dog
tubulin gamma complex associated protein 2
VGNC:53016
480829
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tubulin gamma complex associated protein 2
Macaque
tubulin gamma complex associated protein 2
Mouse
Rat
Dog
tubulin gamma complex associated protein 2
Publication Statistics
PubMed Score 57.85
PubMed score by year
PubTator Score 7.70
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title