Protein Summary
Riboflavin-binding protein which might have a role in retinal flavin transport. This gene was first identified in a study of human eye tissues. The protein encoded by this gene is preferentially expressed in the retina and may play a role in binding retinoids and other carotenoids as it shares homology with riboflavin binding proteins. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
- ENST00000322912
- ENSP00000326253
- ENSG00000132026
- ENST00000393233
- ENSP00000376925
- ENST00000458671
- ENSP00000416375
- ENST00000592204
- ENSP00000466765
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.76 | ||
kinase perturbation | 0.76 | ||
transcription factor | 0.6 | ||
cell line | 0.56 | ||
chemical | 0.43 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.67 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 40 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.67 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 40 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Gene Ontology Terms (5)
Functions (3)
Components (2)
Items per page:
10
1 – 3 of 3
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Protein-Protein Interactions (19)
1 – 10 of 19
GAS6
Novelty: 0.00291371
p_int: 0.999996352
p_ni: 0.000003645
p_wrong: 2e-9
Score: 0.201
Data Source: BioPlex,STRINGDB
ZER1
Novelty: 0.05686147
p_int: 0.993503721
p_ni: 0.006496278
Score: 0.189
Data Source: BioPlex,STRINGDB
TTC19
Novelty: 0.09680022
p_int: 0.986419244
p_ni: 0.013580756
Score: 0.163
Data Source: BioPlex,STRINGDB
COL6A1
Novelty: 0.00861534
p_int: 0.952019363
p_ni: 0.047980637
Score: 0.201
Data Source: BioPlex,STRINGDB
AMD1
Family: Enzyme
Novelty: 0.00107659
p_int: 0.924104667
p_ni: 0.075895331
p_wrong: 2e-9
Score: 0.179
Data Source: BioPlex,STRINGDB
UBAC1
Novelty: 0.00195339
p_int: 0.808997297
p_ni: 0.115236777
p_wrong: 0.075765926
Score: 0.185
Data Source: BioPlex,STRINGDB
TSEN2
Family: Enzyme
Novelty: 0.10246402
p_int: 0.776948047
p_ni: 0.223051952
p_wrong: 1e-9
Score: 0.201
Data Source: BioPlex,STRINGDB
TTC9B
Novelty: 1
Score: 0.584
Data Source: STRINGDB
ERICH1
Novelty: 2.22222222
Score: 0.539
Data Source: STRINGDB
TMEM129
Family: Enzyme
Novelty: 0.40133779
Score: 0.499
Data Source: STRINGDB
Publication Statistics
PubMed Score 4.67
PubMed score by year
PubTator Score 3.33
PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
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