Tbio ATG101 Autophagy-related protein 101

Protein Summary

Description

Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.

Uniprot Accession IDs

• Q9BSB4
• Q9HAE2
• Q9HBN1

Gene Name

• ATG101

Ensembl ID

• ENST00000336854
• ENSP00000338990
• ENSG00000123395

Symbol

• C12orf44
• C12orf44

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.95
histone modification site profile	0.76
transcription factor	0.72
cell line	0.55
tissue sample	0.55

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.91   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 74   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.91   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0