Tbio LLPH Protein LLP homolog

Protein Summary

Description

In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission.

Uniprot Accession IDs

• Q9BRT6
• Q3B766

Gene Name

• LLPH

Ensembl ID

• ENST00000266604
• ENSP00000266604
• ENSG00000139233
• ENST00000446587
• ENSP00000437372

Symbol

• C12orf31
• cPERP-G
• hLLP
• C12orf31

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.9
small molecule perturbation	0.7
kinase perturbation	0.66
transcription factor binding site profile	0.62
tissue	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.87   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 96   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.87   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 96   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0