ADPGK
ADP-dependent glucokinase
Protein Summary
Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity). ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008]
- ENST00000311669
- ENSP00000312250
- ENSG00000159322
- ENST00000456471
- ENSP00000397694
- ENST00000562823
- ENSP00000454367
- ENST00000567941
- ENSP00000458102
- ENST00000569517
- ENSP00000454304
- ADP-GK
- 2610017G09Rik
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor binding site profile | 0.96 | ||
virus perturbation | 0.95 | ||
disease perturbation | 0.9 | ||
cell type or tissue | 0.81 | ||
histone modification site profile | 0.81 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.82 (req: < 5)
Gene RIFs: 10 (req: <= 3)
Antibodies: 195 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.82 (req: >= 5)
Gene RIFs: 10 (req: > 3)
Antibodies: 195 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0