Tbio NUDT22 Uridine diphosphate glucose pyrophosphatase

Protein Summary

Description

Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. Preferred substrate is UDP-glucose.

Uniprot Accession IDs

• Q9BRQ3
• C9JY06
• Q71RD5
• UDPG pyrophosphatase

Gene Name

• NUDT22

Ensembl ID

• ENST00000279206
• ENSP00000279206
• ENSG00000149761
• ENST00000441250
• ENSP00000407970

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.85
cell type or tissue	0.6
kinase perturbation	0.54
tissue	0.53
tissue sample	0.51

Protein Classes

DTO Classes

Uridine Diphosphate Glucose Pyrophosphatase

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.04   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 87   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.04   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0