Tbio MESP1 Mesoderm posterior protein 1

Protein Summary

Description

Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity).

Uniprot Accession IDs

• Q9BRJ9
• Q9NSF1
• Q9NSF2

Gene Name

• MESP1

Ensembl ID

• ENST00000300057
• ENSP00000300057
• ENSG00000166823

Symbol

• BHLHC5
• bHLHc5

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.99
molecular function	0.84
virus perturbation	0.83
transcription factor binding site profile	0.69
tissue sample	0.65

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.91   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 272   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.91   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 272   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 39

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0