Tdark RBM4B RNA-binding protein 4B

Protein Summary

Description

Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA (By similarity).

Uniprot Accession IDs

• Q9BQ04
• B3KT83

Gene Name

• RBM4B

Ensembl ID

• ENST00000310046
• ENSP00000310471
• ENSG00000173914
• ENST00000525754
• ENSP00000433071

Symbol

• RBM30
• RBM30
• RBM4L
• ZCRB3B
• ZCCHC15
• ZCCHC21B

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.94
transcription factor binding site profile	0.85
disease perturbation	0.74
histone modification site profile	0.72
interacting protein	0.69

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Mrna Processing Factor / Mrna Splicing Factor / Rna-binding Protein 4b

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Mrna Processing Factor / Mrna Splicing Factor / Rna-binding Protein 4b

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.11   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 65   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.11   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0