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Tbio
RASL11B
Ras-like protein family member 11B

Protein Summary
Description
RASL11B is a member of the small GTPase protein family with a high degree of similarity to RAS (see HRAS, MIM 190020) proteins.[supplied by OMIM, Nov 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000248706
  • ENSP00000248706
  • ENSG00000128045
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.81
gene perturbation
0.73
molecular function
0.73
PubMedID
0.72
disease perturbation
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.35   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.35   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
ARL9
Tdark
Family:  Enzyme
Novelty:  0.87210932
Score:  0.764
Data Source:  STRINGDB
TMEM68
Tdark
Novelty:  0.61508475
Score:  0.602
Data Source:  STRINGDB
RHOH
Tbio
Family:  Enzyme
Novelty:  0.00882842
Score:  0.597
Data Source:  STRINGDB
MAGI1
Tbio
Family:  Enzyme
Novelty:  0.06837323
Score:  0.567
Data Source:  STRINGDB
ARL5A
Tbio
Family:  Enzyme
Novelty:  0.12410421
Score:  0.544
Data Source:  STRINGDB
PLEK2
Tbio
Novelty:  0.11141066
Score:  0.541
Data Source:  STRINGDB
NTPCR
Tbio
Family:  Enzyme
Novelty:  0.0638186
Score:  0.538
Data Source:  STRINGDB
CD5L
Tbio
Novelty:  0.0095775
Score:  0.493
Data Source:  STRINGDB
RFT1
Tbio
Novelty:  6.81081081
Score:  0.486
Data Source:  STRINGDB
TGFB1
Tbio
Novelty:  0.0001299
Score:  0.485
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cortical surface area measurement
1
2
0
24.9
58.3
1
1
0
1.7
27.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cortical surface area measurement
0
24.9
58.3
0
1.7
27.3
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RAS like family 11 member B
VGNC:7425
738762
Mouse
MGI:1916189
68939
Rat
RGD:1303099
305302
Dog
RAS like family 11 member B
VGNC:51780
100855500
Horse
RAS like family 11 member B
VGNC:22208
100054156
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RAS like family 11 member B
Mouse
Rat
Dog
RAS like family 11 member B
Horse
RAS like family 11 member B
Publication Statistics
PubMed Score 5.35
PubMed score by year
PubTator Score 2.13
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title