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Tchem
P2RY13
P2Y purinoceptor 13

Protein Summary
Description
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000325602
  • ENSP00000320376
  • ENSG00000181631

Symbol
  • GPR86
  • GPR94
  • GPCR1
  • GPR86
  • GPR94
  • P2Y13
  • SP174
  • FKSG77
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.7
gene perturbation
0.65
tissue sample
0.59
ligand (chemical)
0.56
tissue
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.95   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 339   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.95   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 339   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 12
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 3