Tbio VGLL1 Transcription cofactor vestigial-like protein 1

Protein Summary

Description

May act as a specific coactivator for the mammalian TEFs. The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. [provided by RefSeq, Sep 2009]

Uniprot Accession IDs

• Q99990
• Q5H915
• Vgl-1

Gene Name

• VGLL1

Ensembl ID

• ENST00000370634
• ENSP00000359668
• ENSG00000102243

Symbol

• TDU
• TDU
• VGL1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.76
PubMedID	0.61
gene perturbation	0.5
biological process	0.41
cell line	0.39

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Transcription Cofactor Vestigial-like Protein 1

DTO Classes

Protein / Transcription Factor / Transcription Cofactor Vestigial-like Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 199.06   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 105   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 199.06   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0