Protein Summary
May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)-integrin (By similarity).
- ENST00000375550
- ENSP00000364700
- ENSG00000127083
- SLRR2C
- OSAD
- SLRR2C
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
pathway | 0.93 | ||
gene perturbation | 0.68 | ||
kinase perturbation | 0.66 | ||
disease | 0.58 | ||
cellular component | 0.56 | ||
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 54.37 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 161 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 54.37 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 161 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
GWAS Traits (2)
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1 – 2 of 2
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
systolic blood pressure | 1 | 1 | 1 | 56 | |||||
triglyceride measurement | 1 | 1 | 1 | 44.2 | |||||
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
systolic blood pressure | 1 | 56 | |||||
triglyceride measurement | 1 | 44.2 | |||||
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | osteomodulin | VGNC:8917 | 739996 | |||||
Mouse | MGI:1350918 | 27047 | ||||||
Rat | RGD:621818 | 83717 | ||||||
Dog | osteomodulin | VGNC:44122 | 102154566 | |||||
Horse | osteomodulin | VGNC:21032 | 102149475 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | osteomodulin | |||||
Mouse | ||||||
Rat | ||||||
Dog | osteomodulin | |||||
Horse | osteomodulin | |||||
Protein Structure (1 Structure, 1 AlphaFold Model)
Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB
1 – 1 of 1
PDB Structure Id | Ligand | Method | Resolution (Å) | Residues | Fraction of Total Protein | Pub Year | Title |
|---|
PDB Structure Id | Fraction of Total Protein | Resolution | Pub Year |
|---|
Pathways (12)
Reactome (12)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 5 of 12
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) | ||||
Reactome | Defective CHST6 causes MCDC1 | ||||
Reactome | Defective ST3GAL3 causes MCT12 and EIEE15 | ||||
Reactome | Disease | ||||
Reactome | Diseases associated with glycosaminoglycan metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) | ||||
Defective CHST6 causes MCDC1 | ||||
Defective ST3GAL3 causes MCT12 and EIEE15 | ||||
Disease | ||||
Diseases associated with glycosaminoglycan metabolism | ||||
Gene Ontology Terms (9)
Components (5)
Processes (4)
Items per page:
10
1 – 5 of 5
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Protein-Protein Interactions (54)
1 – 10 of 54
APAF1
Family: Enzyme
Novelty: 0.00107622
p_int: 0.999852449
p_ni: 0.000147534
p_wrong: 1.6e-8
Score: 0.24
Data Source: BioPlex,STRINGDB
PATZ1
Family: TF
Novelty: 0.02038599
p_int: 0.973033422
p_ni: 0.026966569
p_wrong: 9e-9
Score: 0.209
Data Source: BioPlex,STRINGDB
BBS1
Novelty: 0.00939439
p_int: 0.911637683
p_ni: 0.088362317
Score: 0.187
Data Source: BioPlex,STRINGDB
SUMF1
Family: Enzyme
Novelty: 0.00954537
p_int: 0.7761673
p_ni: 0.015658529
p_wrong: 0.208174171
Score: 0.237
Data Source: BioPlex,STRINGDB
ACAN
Novelty: 0.00033695
Score: 0.965
Data Source: STRINGDB
OGN
Novelty: 0.00097407
Score: 0.964
Data Source: STRINGDB
FMOD
Novelty: 0.00459438
Score: 0.917
Data Source: STRINGDB
PRELP
Novelty: 0.02849334
Score: 0.914
Data Source: STRINGDB
LUM
Novelty: 0.00219939
Score: 0.911
Data Source: STRINGDB
KERA
Novelty: 0.00789599
Score: 0.907
Data Source: STRINGDB
Publication Statistics
PubMed Score 54.37
PubMed score by year
PubTator Score 8.41
PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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UniProt Keyword
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