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Tbio
FOXC2
Forkhead box protein C2

Protein Summary
Description
Transcriptional activator. Might be involved in the formation of special mesenchymal tissues. This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000320354
  • ENSP00000326371
  • ENSG00000176692
  • ENST00000649859
  • ENSP00000497759

Symbol
  • FKHL14
  • MFH1
  • LD
  • MFH1
  • MFH-1
  • FKHL14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
1
gene perturbation
0.99
ligand (protein) perturbation
0.83
molecular function
0.76
PubMedID
0.74


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 290.05   (req: < 5)
Gene RIFs: 126   (req: <= 3)
Antibodies: 499   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 290.05   (req: >= 5)
Gene RIFs: 126   (req: > 3)
Antibodies: 499   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 26
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0