CCT7
T-complex protein 1 subunit eta
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 1 | ||
kinase perturbation | 1 | ||
co-expressed gene | 0.99 | ||
disease perturbation | 0.97 | ||
hub protein | 0.96 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Association of TriC/CCT with target proteins during biosynthesis | ||||
Reactome | Chaperonin-mediated protein folding | ||||
Reactome | Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | ||||
Reactome | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | ||||
Reactome | Folding of actin by CCT/TriC | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Association of TriC/CCT with target proteins during biosynthesis | ||||
Chaperonin-mediated protein folding | ||||
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | ||||
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | ||||
Folding of actin by CCT/TriC | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
urinary metabolite measurement | 1 | 1 | 2 | 69.5 | |||||
intelligence | 3 | 6 | 2 | 6 | 66.2 | ||||
glomerular filtration rate | 1 | 1 | 1 | 47.7 | |||||
self reported educational attainment | 2 | 2 | 2 | 46.9 | |||||
puberty onset measurement | 1 | 1 | 1 | 17.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
urinary metabolite measurement | 2 | 69.5 | |||||
intelligence | 2 | 6 | 66.2 | ||||
glomerular filtration rate | 1 | 47.7 | |||||
self reported educational attainment | 2 | 46.9 | |||||
puberty onset measurement | 1 | 17.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | chaperonin containing TCP1 subunit 7 | VGNC:186 | 459323 | |||||
Macaque | chaperonin containing TCP1 subunit 7 | 706157 | ||||||
Mouse | MGI:107184 | 12468 | ||||||
Rat | RGD:1306422 | 297406 | ||||||
Dog | T-complex protein 1 subunit eta | 100856782 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | chaperonin containing TCP1 subunit 7 | |||||
Macaque | chaperonin containing TCP1 subunit 7 | |||||
Mouse | ||||||
Rat | ||||||
Dog | T-complex protein 1 subunit eta | |||||
PMID | Year | Title |
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