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Tbio
ZNF184
Zinc finger protein 184

Protein Summary
Description
May be involved in transcriptional regulation. The protein encoded by this gene is predicted to be a Kruppel C2H2-type zinc-finger protein family member. Sequence analysis predicts that the protein contains two Kruppel associated box (KRAB) boxes in the N-terminus and highly conserved zinc finger motifs at the C-terminus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000211936
  • ENSP00000211936
  • ENSG00000096654
  • ENST00000377419
  • ENSP00000366636

Symbol
  • kr-ZNF3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.94
kinase perturbation
0.71
tissue sample
0.66
histone modification site profile
0.65
cell type or tissue
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.06   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.06   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neuroticism measurement
1
1
1
60.6
comparative body size at age 10, self-reported
1
1
1
56.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neuroticism measurement
1
60.6
comparative body size at age 10, self-reported
1
56.8
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (33)
1 – 10 of 33
ZNF324B
Tdark
Family: TF
Novelty: 1.89922228
p_int: 0.998806486
p_ni: 0.001193513
p_wrong: 1e-9
Data Source: BioPlex
PPAN
Tbio
Novelty: 0.01063709
p_int: 0.991173869
p_ni: 0.008775824
p_wrong: 0.000050308
Data Source: BioPlex
RPL23A
Tbio
Novelty: 0.02951947
p_int: 0.983762541
p_ni: 0.016208149
p_wrong: 0.000029311
Data Source: BioPlex
RPL30
Tbio
Novelty: 0.0134194
p_int: 0.977249126
p_ni: 0.022750874
p_wrong: 1e-9
Data Source: BioPlex
HIST1H1E
Tbio
Novelty: 0.01125284
p_int: 0.976510916
p_ni: 0.023489084
Data Source: BioPlex
ZNF777
Tdark
Family: TF
Novelty: 1.20195224
p_int: 0.975357691
p_ni: 0.012452616
p_wrong: 0.012189693
Data Source: BioPlex
WDR46
Tbio
Novelty: 0.19307408
p_int: 0.968831708
p_ni: 0.031135228
p_wrong: 0.000033064
Data Source: BioPlex
CNBP
Tbio
Novelty: 0.00404247
p_int: 0.948693408
p_ni: 0.051297191
p_wrong: 0.000009401
Score: 0.249
Data Source: BioPlex,STRINGDB
RRP8
Tbio
Family: Enzyme
Novelty: 0.04922797
p_int: 0.945860594
p_ni: 0.054131416
p_wrong: 0.00000799
Score: 0.542
Data Source: BioPlex,STRINGDB
THAP3
Tdark
Family: TF
Novelty: 0.52942342
p_int: 0.927716569
p_ni: 0.072066412
p_wrong: 0.00021702
Data Source: BioPlex
Publication Statistics
PubMed Score  5.06

PubMed score by year
PubTator Score  3.02

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer