Tbio CGRRF1 Cell growth regulator with RING finger domain protein 1

Protein Summary

Description

Able to inhibit growth in several cell lines.

Uniprot Accession IDs

• Q99675
• Q96BX2

Gene Name

• CGRRF1

Ensembl ID

• ENST00000216420
• ENSP00000216420
• ENSG00000100532

Symbol

• CGR19
• RNF197
• CGR19
• RNF197

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.76
histone modification site profile	0.7
transcription factor binding site profile	0.68
tissue sample	0.59
gene perturbation	0.53

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.88   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 152   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.88   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 152   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0