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Tbio
EPYC
Epiphycan

Protein Summary
Description
May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization. Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261172
  • ENSP00000261172
  • ENSG00000083782

Symbol
  • DSPG3
  • PGLB
  • SLRR3B
  • PGLB
  • DSPG3
  • Pg-Lb
  • SLRR3B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.78
gene perturbation
0.68
cell line
0.56
disease perturbation
0.43
protein domain
0.41


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 87.19   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 87.19   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
epiphycan
VGNC:5367
452118
Macaque
epiphycan
709645
Mouse
MGI:107942
13516
Rat
RGD:1305904
314772
Dog
epiphycan
VGNC:40431
100855602
Species
Name
OMA
EggNOG
Inparanoid
Chimp
epiphycan
Macaque
epiphycan
Mouse
Rat
Dog
epiphycan
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q99645-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (32)
1 – 10 of 32
ADGRL2
Tbio
Family: GPCR
Novelty: 0.00985539
Score: 0.752
Data Source: STRINGDB
ADGRL1
Tbio
Family: GPCR
Novelty: 0.00957739
Score: 0.713
Data Source: STRINGDB
ADGRL3
Tbio
Family: GPCR
Novelty: 0.00268343
Score: 0.7
Data Source: STRINGDB
LRR1
Tbio
Novelty: 0.02407468
Score: 0.663
Data Source: STRINGDB
LNPEP
Tchem
Family: Enzyme
Novelty: 0.00249049
Score: 0.654
Data Source: STRINGDB
GALE
Tchem
Family: Enzyme
Novelty: 0.00256798
Score: 0.607
Data Source: STRINGDB
STT3B
Tbio
Family: Enzyme
Novelty: 0.05813174
Score: 0.526
Data Source: STRINGDB
LRBA
Tbio
Novelty: 0.00093369
Score: 0.524
Data Source: STRINGDB
SLC35A3
Tbio
Family: Transporter
Novelty: 0.02472244
Score: 0.524
Data Source: STRINGDB
COX7A2
Tbio
Family: Enzyme
Novelty: 0.04287864
Score: 0.509
Data Source: STRINGDB
Publication Statistics
PubMed Score  87.19

PubMed score by year
PubTator Score  9.56

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer