Tbio EPYC Epiphycan

Protein Summary

Description

May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization. Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q99645
• A8K3M7
• Q8NEJ5

Gene Name

• EPYC

Ensembl ID

• ENST00000261172
• ENSP00000261172
• ENSG00000083782

Symbol

• DSPG3
• PGLB
• SLRR3B
• PGLB
• DSPG3
• Pg-Lb
• SLRR3B

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.78
gene perturbation	0.68
cell line	0.56
disease perturbation	0.43
protein domain	0.41

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 154.59   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 114   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 154.59   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0