EIF3C
Eukaryotic translation initiation factor 3 subunit C
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 1 | ||
drug perturbation | 0.99 | ||
small molecule perturbation | 0.99 | ||
disease perturbation | 0.96 | ||
transcription factor perturbation | 0.96 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | ||||
Reactome | Cap-dependent Translation Initiation | ||||
Reactome | Eukaryotic Translation Initiation | ||||
Reactome | Formation of a pool of free 40S subunits | ||||
Reactome | Formation of the ternary complex, and subsequently, the 43S complex | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | ||||
Cap-dependent Translation Initiation | ||||
Eukaryotic Translation Initiation | ||||
Formation of a pool of free 40S subunits | ||||
Formation of the ternary complex, and subsequently, the 43S complex | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-UniRule | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
intelligence | 5 | 11 | 6 | 6.6 | 94 | ||||
red blood cell density measurement | 1 | 1 | 1 | 81.6 | |||||
cognitive function measurement | 1 | 1 | 1 | 81.3 | |||||
self reported educational attainment | 2 | 2 | 1 | 7.6 | 72.4 | ||||
body fat percentage | 1 | 1 | 2 | 68 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
intelligence | 6 | 6.6 | 94 | ||||
red blood cell density measurement | 1 | 81.6 | |||||
cognitive function measurement | 1 | 81.3 | |||||
self reported educational attainment | 1 | 7.6 | 72.4 | ||||
body fat percentage | 2 | 68 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | eukaryotic translation initiation factor 3 subunit C | 705696 | ||||||
Mouse | MGI:1926966 | 56347 | ||||||
Rat | RGD:1308871 | 293484 | ||||||
Cow | eukaryotic translation initiation factor 3, subunit C-like | 534882 | ||||||
Anole lizard | eukaryotic translation initiation factor 3 subunit C | 100555291 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | eukaryotic translation initiation factor 3 subunit C | |||||
Mouse | ||||||
Rat | ||||||
Cow | eukaryotic translation initiation factor 3, subunit C-like | |||||
Anole lizard | eukaryotic translation initiation factor 3 subunit C | |||||
PMID | Year | Title |
---|