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Tbio
KLF6
Krueppel-like factor 6

Protein Summary
Description
Transcriptional activator (By similarity). Binds a GC box motif. Could play a role in B-cell growth and development. This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis. [provided by RefSeq, May 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000469435
  • ENSP00000419079
  • ENSG00000067082
  • ENST00000497571
  • ENSP00000419923
  • ENST00000542957
  • ENSP00000445301

Symbol
  • BCD1
  • COPEB
  • CPBP
  • ST12
  • GBF
  • ZF9
  • BCD1
  • CBA1
  • CPBP
  • PAC1
  • ST12
  • COPEB
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
1
transcription factor perturbation
1
virus perturbation
0.97
transcription factor binding site profile
0.96
disease perturbation
0.93


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 455.13   (req: < 5)
Gene RIFs: 177   (req: <= 3)
Antibodies: 197   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 455.13   (req: >= 5)
Gene RIFs: 177   (req: > 3)
Antibodies: 197   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0