PCYT2
Ethanolamine-phosphate cytidylyltransferase
Protein Summary
Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine. This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
- ENST00000331285
- ENSP00000331719
- ENSG00000185813
- ENST00000538721
- ENSP00000442050
- ENST00000538936
- ENSP00000439245
- ENST00000570388
- ENSP00000458330
- ENST00000570391
- ENSP00000461190
- ET
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
disease perturbation | 1 | ||
transcription factor | 0.78 | ||
transcription factor binding site profile | 0.64 | ||
tissue sample | 0.62 | ||
small molecule perturbation | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 44.27 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 119 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 44.27 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 119 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0