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Tdark
DSCR8
Down syndrome critical region protein 8

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.96   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.96   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein-Protein Interactions (16)
1 – 10 of 16
DSCR4
Tdark
Novelty: 0.06035045
Score: 0.889
Data Source: STRINGDB
GFER
Tchem
Family: Enzyme
Novelty: 0.00338563
Score: 0.716
Data Source: STRINGDB
KCNJ6
Tchem
Family: IC
Novelty: 0.00330353
Score: 0.61
Data Source: STRINGDB
KCNJ15
Tbio
Family: IC
Novelty: 0.03299706
Score: 0.594
Data Source: STRINGDB
LCA5L
Tdark
Novelty: 0.65812628
Score: 0.566
Data Source: STRINGDB
MMD
Tbio
Novelty: 0.02646322
Score: 0.53
Data Source: STRINGDB
RIPPLY3
Tdark
Novelty: 0.13457311
Score: 0.511
Data Source: STRINGDB
PSMG1
Tbio
Novelty: 0.08175356
Score: 0.505
Data Source: STRINGDB
ABCD4
Tbio
Family: Transporter
Novelty: 0.04096359
Score: 0.482
Data Source: STRINGDB
PIGP
Tbio
Family: Enzyme
Novelty: 0.01400934
Score: 0.445
Data Source: STRINGDB
Publication Statistics
PubMed Score  16.96

PubMed score by year
PubTator Score  11.53

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer