You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TMEM209
Transmembrane protein 209

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000397622
  • ENSP00000380747
  • ENSG00000146842
  • ENST00000462753
  • ENSP00000419697
  • ENST00000473456
  • ENSP00000417258

Symbol
  • NET31
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.94
histone modification site profile
0.9
small molecule perturbation
0.75
transcription factor binding site profile
0.72
kinase perturbation
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.67   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.67   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (62)
TMEM126A
Tbio
Novelty:  0.11759225
Score:  0.784
Data Source:  STRINGDB
TMUB1
Tbio
Novelty:  0.11851789
Score:  0.782
Data Source:  STRINGDB
NUP153
Tbio
Novelty:  0.00696568
Score:  0.734
Data Source:  STRINGDB
TMEM199
Tbio
Novelty:  0.05799147
Score:  0.726
Data Source:  STRINGDB
CYBC1
Tdark
Novelty:  0.72567331
Score:  0.668
Data Source:  STRINGDB
FBXO43
Tbio
Novelty:  0.04056148
Score:  0.658
Data Source:  STRINGDB
FNDC3A
Tbio
Novelty:  0.04721453
Score:  0.651
Data Source:  STRINGDB
ERG28
Tbio
Novelty:  0.04267481
Score:  0.64
Data Source:  STRINGDB
PPP1R8
Tbio
Family:  Enzyme
Novelty:  0.00138054
Score:  0.634
Data Source:  STRINGDB
CCDC58
Tdark
Novelty:  1.40672371
Score:  0.626
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
asparaginase-induced acute pancreatitis
1
1
0
6.6
46.9
BMI-adjusted hip circumference
1
1
1
37.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
asparaginase-induced acute pancreatitis
0
6.6
46.9
BMI-adjusted hip circumference
1
37.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 209
VGNC:14468
463725
Macaque
transmembrane protein 209
706578
Mouse
MGI:1919899
72649
Rat
RGD:1309682
312200
Dog
transmembrane protein 209
VGNC:47528
475194
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 209
Macaque
transmembrane protein 209
Mouse
Rat
Dog
transmembrane protein 209
Publication Statistics
PubMed Score 4.67
PubMed score by year
PubTator Score 0.67
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title