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Tbio
KCTD15
BTB/POZ domain-containing protein KCTD15

Protein Summary
Description
During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000284006
  • ENSP00000284006
  • ENSG00000153885
  • ENST00000430256
  • ENSP00000394390
  • ENST00000588881
  • ENSP00000464812
  • ENST00000589786
  • ENSP00000467612
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.95
microRNA
0.89
transcription factor
0.82
PubMedID
0.77
transcription factor binding site profile
0.77


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.78   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 237   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.78   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 237   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0