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Tdark
CCT8L2
T-complex protein 1 subunit theta-like 2

Protein Classes
Protein Summary
Description
Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000359963
  • ENSP00000353048
  • ENSG00000198445

Symbol
  • CESK1
  • CESK1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
1
gene perturbation
0.86
protein domain
0.73
cell line
0.55
tissue sample
0.46


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 373   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.21   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 373   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chaperonin containing TCP1 subunit 8 like 2
470129
Mouse
MGI:2685289
242891
Rat
Dog
chaperonin containing TCP1 subunit 8 like 2
482811
Cow
chaperonin containing TCP1 subunit 8 like 2
618575
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chaperonin containing TCP1 subunit 8 like 2
Mouse
Rat
Dog
chaperonin containing TCP1 subunit 8 like 2
Cow
chaperonin containing TCP1 subunit 8 like 2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96SF2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (52)
1 – 10 of 52
BBS10
Tbio
Novelty: 0.03343798
Score: 0.995
Data Source: STRINGDB
CCT7
Tbio
Novelty: 0.02247038
Score: 0.973
Data Source: STRINGDB
CCT3
Tbio
Novelty: 0.01642521
Score: 0.972
Data Source: STRINGDB
CCT4
Tbio
Novelty: 0.01176123
Score: 0.969
Data Source: STRINGDB
CCT2
Tbio
Novelty: 0.01967139
Score: 0.966
Data Source: STRINGDB
CCT5
Tbio
Novelty: 0.02369118
Score: 0.956
Data Source: STRINGDB
MKKS
Tbio
Novelty: 0.00805347
Score: 0.892
Data Source: STRINGDB
CCT6A
Tbio
Novelty: 0.02368046
Score: 0.891
Data Source: STRINGDB
CCT6B
Tdark
Novelty: 0.28933315
Score: 0.889
Data Source: STRINGDB
BBS12
Tbio
Novelty: 0.06131428
Score: 0.887
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.21

PubMed score by year
PubTator Score  0.25

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer