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Tdark
UBL7
Ubiquitin-like protein 7

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361351
  • ENSP00000354883
  • ENSG00000138629
  • ENST00000395081
  • ENSP00000378518
  • ENST00000564488
  • ENSP00000454828
  • ENST00000565335
  • ENSP00000457708
  • ENST00000567435
  • ENSP00000457703

Symbol
  • BMSCUBP
  • TCBA1
  • BMSC-UbP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
transcription factor binding site profile
0.91
protein domain
0.85
kinase perturbation
0.81
transcription factor
0.77


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.98   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.98   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
caffeine metabolite measurement
3
2
0
7.2
68.4
apolipoprotein A 1 measurement
1
1
1
56
high density lipoprotein cholesterol measurement
2
1
2
55.2
Cleft palate
1
1
0
1.2
47.7
1
1
0
1.2
47.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
caffeine metabolite measurement
0
7.2
68.4
apolipoprotein A 1 measurement
1
56
high density lipoprotein cholesterol measurement
2
55.2
Cleft palate
0
1.2
47.7
0
1.2
47.7
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ubiquitin like 7
VGNC:6455
453740
Mouse
MGI:1916709
69459
Rat
RGD:1303055
300744
Dog
ubiquitin like 7
VGNC:48079
478366
Horse
ubiquitin like 7
VGNC:51830
100062522
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ubiquitin like 7
Mouse
Rat
Dog
ubiquitin like 7
Horse
ubiquitin like 7
Protein Structure (2 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q96S82-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 2 of 2
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Protein-Protein Interactions (215)
1 – 10 of 215
UBE4B
Tbio
Novelty:  0.01396546
p_int:  1
Score:  0.928
Data Source:  BioPlex,STRINGDB
OR7A5
Tdark
Family:  oGPCR
Novelty:  1.72860482
p_int:  0.999990461
p_ni:  0.000006492
p_wrong:  0.000003047
Data Source:  BioPlex
VBP1
Tbio
Novelty:  0.0428293
p_int:  0.999962886
p_ni:  0.000037114
Score:  0.298
Data Source:  BioPlex,STRINGDB
RAD23B
Tbio
Novelty:  0.00672104
p_int:  0.999809485
p_ni:  0.000190515
Score:  0.853
Data Source:  BioPlex,STRINGDB
HDAC6
Tclin
Family:  Epigenetic
Novelty:  0.00122232
p_int:  0.999675342
p_ni:  0.000324148
p_wrong:  5.1e-7
Score:  0.613
Data Source:  BioPlex,STRINGDB
VCP
Tchem
Family:  Enzyme
Novelty:  0.00103317
p_int:  0.999579606
p_ni:  0.000420394
Score:  0.676
Data Source:  BioPlex,STRINGDB
UBB
Tbio
Novelty:  0.00661254
p_int:  0.999366173
p_ni:  0.000633827
Score:  0.385
Data Source:  BioPlex,STRINGDB
OR2G6
Tdark
Family:  oGPCR
p_int:  0.99730014
p_ni:  0.000068954
p_wrong:  0.002630906
Data Source:  BioPlex
KDELR1
Tbio
Novelty:  0.0036468
p_int:  0.997184229
p_ni:  0.002763745
p_wrong:  0.000052026
Score:  0.178
Data Source:  BioPlex,STRINGDB
AMY1A
Tchem
Family:  Enzyme
Novelty:  0.00210045
p_int:  0.957214752
p_ni:  0.042785248
Data Source:  BioPlex
Publication Statistics
PubMed Score  3.98

PubMed score by year
PubTator Score  3

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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