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Tbio
CLCC1
Chloride channel CLIC-like protein 1

Protein Summary
Description
Seems to act as a chloride ion channel.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000302500
  • ENSP00000306552
  • ENSG00000121940
  • ENST00000348264
  • ENSP00000337243
  • ENST00000356970
  • ENSP00000349456
  • ENST00000369968
  • ENSP00000358985
  • ENST00000369969
  • ENSP00000358986
  • ENST00000369970
  • ENSP00000358987

Symbol
  • KIAA0761
  • MCLC
  • MCLC
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.84
kinase perturbation
0.81
tissue sample
0.64
transcription factor binding site profile
0.62
cellular component
0.6


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.79   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 127   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.79   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chloride channel CLIC like 1
VGNC:6736
457081
Macaque
chloride channel CLIC like 1
696577
Mouse
MGI:2385186
229725
Rat
RGD:708359
170927
Dog
chloride channel CLIC like 1
VGNC:39299
479918
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chloride channel CLIC like 1
Macaque
chloride channel CLIC like 1
Mouse
Rat
Dog
chloride channel CLIC like 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96S66-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (85)
1 – 10 of 85
DAZAP2
Tbio
Novelty: 0.02387823
p_int: 0.999993526
p_ni: 0.000006454
p_wrong: 2.1e-8
Score: 0.209
Data Source: BioPlex,STRINGDB
GMCL1
Tbio
Novelty: 0.1543762
p_int: 0.999962261
p_ni: 0.000037738
p_wrong: 1e-9
Data Source: BioPlex
PLSCR1
Tbio
Family: Enzyme
Novelty: 0.01483138
p_int: 0.999939215
p_ni: 0.000053575
p_wrong: 0.000007211
Score: 0.189
Data Source: BioPlex,STRINGDB
TBCE
Tbio
Novelty: 0.01058281
p_int: 0.989606537
p_ni: 0.010382489
p_wrong: 0.000010974
Score: 0.189
Data Source: BioPlex,STRINGDB
UBR1
Tbio
Family: Enzyme
Novelty: 0.00998888
p_int: 0.899267101
p_ni: 0.100732899
Data Source: BioPlex
TSPAN15
Tbio
Novelty: 0.16947672
p_int: 0.875030937
p_ni: 0.10460226
p_wrong: 0.020366803
Score: 0.177
Data Source: BioPlex,STRINGDB
SEMA7A
Tbio
Novelty: 0.00741605
p_int: 0.842401704
p_ni: 0.157598296
Score: 0.173
Data Source: BioPlex,STRINGDB
TMBIM6
Tbio
Novelty: 0.00151958
p_int: 0.827489549
p_ni: 0.172510444
p_wrong: 7e-9
Data Source: BioPlex
SPNS3
Tdark
Novelty: 0.40832952
p_int: 0.807033927
p_ni: 0.192966073
Score: 0.455
Data Source: BioPlex,STRINGDB
PTPRG
Tchem
Family: Enzyme
Novelty: 0.01920574
p_int: 0.782618081
p_ni: 0.217381918
p_wrong: 1e-9
Data Source: BioPlex
Publication Statistics
PubMed Score  16.79

PubMed score by year
PubTator Score  3.5

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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