Tbio CLCC1 Chloride channel CLIC-like protein 1

Protein Summary

Description

Seems to act as a chloride ion channel.

Uniprot Accession IDs

• Q96S66
• O94861
• Q8WYP8
• Q8WYP9
• Q9BU25

Gene Name

• CLCC1

Ensembl ID

• ENST00000302500
• ENSP00000306552
• ENSG00000121940
• ENST00000348264
• ENSP00000337243
• ENST00000356970
• ENSP00000349456
• ENST00000369968
• ENSP00000358985
• ENST00000369969
• ENSP00000358986
• ENST00000369970
• ENSP00000358987

Symbol

• KIAA0761
• MCLC
• MCLC

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.84
kinase perturbation	0.81
tissue sample	0.64
transcription factor binding site profile	0.62
cellular component	0.6

Protein Classes

DTO Classes

Protein / Ion Channel / Intracellular Chloride Channel (Icc) Family / Chloride Channel Clic-like Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.93   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 127   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.93   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0