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Tbio
TUBGCP5
Gamma-tubulin complex component 5

Protein Summary
Description
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000615383
  • ENSP00000480316
  • ENSG00000275835
  • ENST00000620435
  • ENSP00000481853

Symbol
  • GCP5
  • KIAA1899
  • GCP5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
cellular component
0.78
kinase perturbation
0.71
cell line
0.65
transcription factor binding site profile
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.41   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 125   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.41   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 125   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (10)
Cell Cycle (R-HSA-1640170)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 9
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cell Cycle
Reactome
Cell Cycle, Mitotic
Reactome
Centrosome maturation
Reactome
G2/M Transition
Reactome
M Phase
Name
Explore in Pharos
Explore in Source
Cell Cycle
Cell Cycle, Mitotic
Centrosome maturation
G2/M Transition
M Phase
Gene Ontology Terms (16)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (132)
1 – 10 of 132
TUBG2
Tbio
Novelty: 0.23300971
p_int: 1
Score: 0.989
Data Source: BioPlex,STRINGDB
MZT2B
Tdark
Novelty: 4
p_int: 0.999999998
p_ni: 2e-9
Score: 0.998
Data Source: BioPlex,STRINGDB
MZT1
Tdark
Novelty: 0.14016352
p_int: 0.999999567
p_ni: 4.32e-7
p_wrong: 1e-9
Score: 0.998
Data Source: BioPlex,STRINGDB
TUBGCP6
Tbio
Novelty: 0.14014014
p_int: 0.999998367
p_ni: 0.000001632
p_wrong: 1e-9
Score: 0.996
Data Source: BioPlex,STRINGDB
TUBGCP4
Tbio
Novelty: 0.01120518
p_int: 0.999991653
p_ni: 0.000008175
p_wrong: 1.72e-7
Score: 0.999
Data Source: BioPlex,STRINGDB
TUBGCP3
Tbio
Novelty: 0.0308076
p_int: 0.999948615
p_ni: 0.000051385
Score: 0.995
Data Source: BioPlex,STRINGDB
TXNDC12
Tbio
Novelty: 0.02131718
p_int: 0.999943078
p_ni: 0.000056904
p_wrong: 1.7e-8
Score: 0.859
Data Source: BioPlex,STRINGDB
TUBGCP2
Tbio
Novelty: 0.03216604
p_int: 0.999852587
p_ni: 0.000147413
Score: 0.992
Data Source: BioPlex,STRINGDB
MZT2A
Tdark
Novelty: 4
p_int: 0.99984909
p_ni: 4.7e-8
p_wrong: 0.000150863
Score: 0.996
Data Source: BioPlex,STRINGDB
TUBG1
Tbio
Novelty: 0.03880643
p_int: 0.999603713
p_ni: 0.000396287
Score: 0.993
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  7.41

PubMed score by year
PubTator Score  6.8

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer