Tbio TUBGCP5 Gamma-tubulin complex component 5

Protein Summary

Description

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.

Uniprot Accession IDs

• Q96RT8
• E9PB12
• Q6IQ52
• Q96PY8
• GCP-5

Gene Name

• TUBGCP5

Ensembl ID

• ENST00000615383
• ENSP00000480316
• ENSG00000275835
• ENST00000620435
• ENSP00000481853

Symbol

• GCP5
• KIAA1899
• GCP5

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.86
cellular component	0.78
kinase perturbation	0.71
cell line	0.65
transcription factor binding site profile	0.63

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Non-motor Microtubule Binding Protein / Gamma-tubulin Complex Component 5

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Non-motor Microtubule Binding Protein / Gamma-tubulin Complex Component 5

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.06   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 125   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.06   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 125   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0