Tbio TUBGCP6 Gamma-tubulin complex component 6

Protein Summary

Description

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. The protein encoded by this gene is part of a large multisubunit complex required for microtubule nucleation at the centrosome. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q96RT7
• Q5JZ80
• Q6PJ40
• Q86YE9
• Q9BY91
• Q9UGX3
• Q9UGX4
• GCP-6

Gene Name

• TUBGCP6

Ensembl ID

• ENST00000248846
• ENSP00000248846
• ENSG00000128159

Symbol

• GCP6
• KIAA1669
• GCP6
• GCP-6
• MCCRP
• MCCRP1
• MCPHCR

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.81
interacting protein	0.64
transcription factor binding site profile	0.62
tissue sample	0.61
tissue	0.56

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Non-motor Microtubule Binding Protein / Gamma-tubulin Complex Component 6

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Non-motor Microtubule Binding Protein / Gamma-tubulin Complex Component 6

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.24   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 106   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.24   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0