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Tbio
RBP7
Retinoid-binding protein 7

Protein Summary
Description
Intracellular transport of retinol. The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294435
  • ENSP00000294435
  • ENSG00000162444

Symbol
  • CRBP4
  • CRABP4
  • CRBPIV
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.76
cell type or tissue
0.74
tissue sample
0.67
small molecule perturbation
0.63
protein domain
0.58


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.89   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.89   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
retinol binding protein 7
VGNC:6974
101057726
Macaque
retinol binding protein 7 [Source:HGNC Symbol;Acc:HGNC:30316]
Mouse
MGI:1890409
63954
Rat
RGD:1562168
362662
Dog
retinol binding protein 7
VGNC:53436
479602
Species
Name
OMA
EggNOG
Inparanoid
Chimp
retinol binding protein 7
Macaque
retinol binding protein 7 [Source:HGNC Symbol;Acc:HGNC:30316]
Mouse
Rat
Dog
retinol binding protein 7
Protein Structure (2 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q96R05-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 2 of 2
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (34)
1 – 10 of 34
UBE4B
Tbio
Novelty: 0.01396546
Score: 0.562
Data Source: STRINGDB
GPR157
Tdark
Family: GPCR
Novelty: 0.96671087
Score: 0.554
Data Source: STRINGDB
TMEM201
Tbio
Novelty: 0.00616362
Score: 0.547
Data Source: STRINGDB
SLC45A1
Tdark
Family: Transporter
Novelty: 0.15556432
Score: 0.547
Data Source: STRINGDB
POLR2G
Tbio
Family: Enzyme
Novelty: 0.01235379
Score: 0.541
Data Source: STRINGDB
SOCS4
Tbio
Novelty: 0.01633743
Score: 0.54
Data Source: STRINGDB
SOCS7
Tbio
Novelty: 0.01296916
Score: 0.526
Data Source: STRINGDB
NMNAT1
Tbio
Family: Enzyme
Novelty: 0.01110899
Score: 0.523
Data Source: STRINGDB
PIK3R3
Tbio
Family: Enzyme
Novelty: 0.0136069
Score: 0.521
Data Source: STRINGDB
SLC25A33
Tbio
Family: Transporter
Novelty: 0.17554778
Score: 0.518
Data Source: STRINGDB
Publication Statistics
PubMed Score  15.89

PubMed score by year
PubTator Score  7.15

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer