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Tbio
RBP7
Retinoid-binding protein 7

Protein Summary
Description
Intracellular transport of retinol. The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294435
  • ENSP00000294435
  • ENSG00000162444

Symbol
  • CRBP4
  • CRABP4
  • CRBPIV
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.76
cell type or tissue
0.74
tissue sample
0.67
small molecule perturbation
0.63
protein domain
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.95   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.95   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (2)
1 – 2 of 2
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (34)
1 – 10 of 34
UBE4B
Tbio
Novelty: 0.01303629
Score: 0.562
Data Source: STRINGDB
GPR157
Tdark
Family: GPCR
Novelty: 0.9
Score: 0.554
Data Source: STRINGDB
TMEM201
Tbio
Novelty: 0.00740939
Score: 0.547
Data Source: STRINGDB
SLC45A1
Tdark
Family: Transporter
Novelty: 0.29991441
Score: 0.547
Data Source: STRINGDB
POLR2G
Tbio
Family: Enzyme
Novelty: 0.01513348
Score: 0.541
Data Source: STRINGDB
SOCS4
Tbio
Novelty: 0.02588852
Score: 0.54
Data Source: STRINGDB
SOCS7
Tbio
Novelty: 0.01339163
Score: 0.526
Data Source: STRINGDB
NMNAT1
Tbio
Family: Enzyme
Novelty: 0.01416255
Score: 0.523
Data Source: STRINGDB
PIK3R3
Tbio
Family: Enzyme
Novelty: 0.02218437
Score: 0.521
Data Source: STRINGDB
SLC25A33
Tbio
Family: Transporter
Novelty: 0.2689124
Score: 0.518
Data Source: STRINGDB
Publication Statistics
PubMed Score  21.95

PubMed score by year
PubTator Score  7.15

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer