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Tbio
MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

Protein Summary
Description
May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity). The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000330909
  • ENSP00000331157
  • ENSG00000151276
  • ENST00000402939
  • ENSP00000385450
  • ENST00000483466
  • ENSP00000420323
  • ENST00000497477
  • ENSP00000424369
  • ENST00000634409
  • ENSP00000489444
  • ENSG00000282956
  • ENST00000634774
  • ENSP00000489393
  • ENST00000635378
  • ENSP00000489391
  • ENST00000635471
  • ENSP00000489322

Symbol
  • AIP3
  • BAIAP1
  • BAP1
  • TNRC19
  • AIP3
  • BAP1
  • WWP3
  • AIP-3
  • BAP-1
  • BAIAP1
  • MAGI-1
  • Magi1d
  • TNRC19
  • MAGI-1b
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
viral protein
1
virus
1
trait
0.97
protein domain
0.92
disease perturbation
0.9


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.92   (req: < 5)
Gene RIFs: 25   (req: <= 3)
Antibodies: 179   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.92   (req: >= 5)
Gene RIFs: 25   (req: > 3)
Antibodies: 179   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0