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Tdark
LRRC37B
Leucine-rich repeat-containing protein 37B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341671
  • ENSP00000340519
  • ENSG00000185158
  • ENST00000394713
  • ENSP00000378202

Symbol
  • LRRC37
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.9
tissue
0.67
tissue sample
0.63
cell type or tissue
0.59
cell line
0.53


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.03   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.03   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
1
1
1
40.7
body height
1
1
1
17.8
red blood cell distribution width
1
1
1
17.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
1
40.7
body height
1
17.8
red blood cell distribution width
1
17.7
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
leucine-rich repeat-containing protein 37B
749894
Species
Name
OMA
EggNOG
Inparanoid
Chimp
leucine-rich repeat-containing protein 37B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96QE4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (19)
1 – 10 of 19
LAPTM4B
Tbio
Novelty:  0.01162533
Score:  0.794
Data Source:  STRINGDB
UTP6
Tbio
Novelty:  0.06525007
Score:  0.589
Data Source:  STRINGDB
ADAP2
Tbio
Novelty:  0.11270592
Score:  0.574
Data Source:  STRINGDB
CRLF3
Tbio
Novelty:  0.17318857
Score:  0.559
Data Source:  STRINGDB
ANKRD13B
Tdark
Novelty:  1.45055536
Score:  0.558
Data Source:  STRINGDB
TEFM
Tbio
Novelty:  0.10836617
Score:  0.533
Data Source:  STRINGDB
ATAD5
Tbio
Family:  Enzyme
Novelty:  0.02459839
Score:  0.529
Data Source:  STRINGDB
TMEM255B
Tdark
Novelty:  1.57149427
Score:  0.529
Data Source:  STRINGDB
EVI2A
Tbio
Novelty:  0.02320553
Score:  0.509
Data Source:  STRINGDB
FAM208A
Tbio
Novelty:  0.17789689
Score:  0.495
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.03

PubMed score by year
PubTator Score  0.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer