SLC2A13
Proton myo-inositol cotransporter
Protein Summary
H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.
- ENST00000280871
- ENSP00000280871
- ENSG00000151229
- HMIT
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
trait | 0.93 | ||
histone modification site profile | 0.78 | ||
transcription factor perturbation | 0.74 | ||
transcription factor binding site profile | 0.67 | ||
cell type or tissue | 0.62 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 17.44 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 109 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 17.44 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 109 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (165)
RIOK3
Family: Kinase
Novelty: 0.07513953
p_int: 0.999995102
p_ni: 0.000004822
p_wrong: 7.6e-8
Data Source: BioPlex
ATG9A
Novelty: 0.01995033
p_int: 0.874777766
p_ni: 0.125219205
p_wrong: 0.000003029
Data Source: BioPlex
BLK
Family: Kinase
Novelty: 0.00480349
p_int: 0.815024164
p_ni: 0.180591899
p_wrong: 0.004383937
Data Source: BioPlex
Nearest Tclin Targets
Pathways (6)
Reactome (4)
WikiPathways (2)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Inositol transporters | ||||
Reactome | SLC-mediated transmembrane transport | ||||
Reactome | Transport of bile salts and organic acids, metal ions and amine compounds | ||||
Reactome | Transport of small molecules | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Inositol transporters | ||||
SLC-mediated transmembrane transport | ||||
Transport of bile salts and organic acids, metal ions and amine compounds | ||||
Transport of small molecules | ||||
Viral Interactions (0)
Gene Ontology Terms (4)
Functions (1)
Components (2)
Processes (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations ()
GWAS Traits (4)
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
3 | 3 | 1 | 1.5 | 91.3 | |||||
low density lipoprotein cholesterol measurement | 2 | 2 | 2 | 61.3 | |||||
mean platelet volume | 1 | 1 | 1 | 36.9 | |||||
1 | 1 | 0 | 1.5 | 32.7 | |||||
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
1 | 1.5 | 91.3 | |||||
low density lipoprotein cholesterol measurement | 2 | 61.3 | |||||
mean platelet volume | 1 | 36.9 | |||||
0 | 1.5 | 32.7 | |||||
Find similar targets by:
IDG Resources
Orthologs (13)
1 – 5 of 13
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | solute carrier family 2 member 13 | VGNC:8538 | 466953 | |||||
Macaque | solute carrier family 2 member 13 | 697822 | ||||||
Mouse | MGI:2146030 | 239606 | ||||||
Rat | RGD:621814 | 171147 | ||||||
Dog | solute carrier family 2 member 13 | VGNC:46340 | 486609 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | solute carrier family 2 member 13 | |||||
Macaque | solute carrier family 2 member 13 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 2 member 13 | |||||
Publication Statistics
PubMed Score 17.44
PubMed score by year
PubTator Score 8.76
PubTator score by year
Related Publications
Text Mined References (15)
GeneRif Annotations (5)
Items per page:
0 of 0
PMID | Year | Title |
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