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Tbio
FYTTD1
UAP56-interacting factor

Protein Summary
Description
Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000241502
  • ENSP00000241502
  • ENSG00000122068
  • ENST00000415708
  • ENSP00000393746
  • ENST00000418169
  • ENSP00000400191
  • ENST00000424384
  • ENSP00000394631

Symbol
  • UIF
  • UIF
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
interacting protein
0.87
transcription factor binding site profile
0.78
virus perturbation
0.68
small molecule perturbation
0.63


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.73   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 130   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.73   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 130   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
forty-two-three domain containing 1
VGNC:11974
744356
Mouse
MGI:1917955
69823
Rat
RGD:1306899
360726
Dog
forty-two-three domain containing 1
100856482
Horse
forty-two-three domain containing 1
VGNC:18169
100060393
Species
Name
OMA
EggNOG
Inparanoid
Chimp
forty-two-three domain containing 1
Mouse
Rat
Dog
forty-two-three domain containing 1
Horse
forty-two-three domain containing 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96QD9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (8)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Metabolism of RNA
Reactome
Processing of Capped Intron-Containing Pre-mRNA
Reactome
RNA Polymerase II Transcription
Reactome
RNA Polymerase II Transcription Termination
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Metabolism of RNA
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
RNA Polymerase II Transcription Termination
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (142)
1 – 10 of 142
SARNP
Tbio
Novelty:  0.00987312
p_int:  0.999111207
p_ni:  0.000888793
Score:  0.979
Data Source:  BioPlex,STRINGDB
NKAPD1
Tdark
Novelty:  1.56979675
p_int:  0.998584877
p_ni:  0.001415123
Data Source:  BioPlex
CHTOP
Tbio
Novelty:  0.04170391
p_int:  0.997592218
p_ni:  0.002407782
Score:  0.984
Data Source:  BioPlex,STRINGDB
CCNYL1
Tdark
Novelty:  0.45350824
p_int:  0.995540114
p_ni:  0.004455662
p_wrong:  0.000004224
Data Source:  BioPlex
ERICH5
Tdark
Novelty:  5.57504212
p_int:  0.995078637
p_ni:  0.004921359
p_wrong:  4e-9
Data Source:  BioPlex
LASP1
Tbio
Novelty:  0.00960538
p_int:  0.98639218
p_ni:  0.01360782
Score:  0.294
Data Source:  BioPlex,STRINGDB
OCC1
Tbio
Novelty:  0.05175429
p_int:  0.985915633
p_ni:  0.010354648
p_wrong:  0.003729719
Data Source:  BioPlex
PTPRG
Tchem
Family:  Enzyme
Novelty:  0.01920574
p_int:  0.971714309
p_ni:  0.028285691
Score:  0.155
Data Source:  BioPlex,STRINGDB
PLS1
Tbio
Novelty:  0.00538817
p_int:  0.971298097
p_ni:  0.028701903
Data Source:  BioPlex
GNAQ
Tbio
Novelty:  0.0008997
p_int:  0.958894259
p_ni:  0.041105741
Data Source:  BioPlex
Publication Statistics
PubMed Score  20.73

PubMed score by year
PubTator Score  2.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
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