You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
YPEL2
Protein yippee-like 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000312655
  • ENSP00000312272
  • ENSG00000175155
  • ENST00000585166
  • ENSP00000464285

Symbol
  • FKSG4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.97
cell type or tissue
0.83
transcription factor binding site profile
0.83
histone modification site profile
0.69
microRNA
0.66


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.57   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.57   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
3
3
3
84.1
mean corpuscular volume
1
1
1
80.3
HbA1c measurement
1
2
2
76.6
eosinophil count
1
1
1
68.6
reticulocyte measurement
1
1
1
61
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
3
84.1
mean corpuscular volume
1
80.3
HbA1c measurement
2
76.6
eosinophil count
1
68.6
reticulocyte measurement
1
61
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
yippee like 2
VGNC:9794
735409
Mouse
MGI:1925114
77864
Dog
yippee like 2
VGNC:48498
610066
Horse
yippee like 2
VGNC:25108
100057281
Cow
yippee like 2
VGNC:37035
616180
Species
Name
OMA
EggNOG
Inparanoid
Chimp
yippee like 2
Mouse
Dog
yippee like 2
Horse
yippee like 2
Cow
yippee like 2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96QA6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (26)
1 – 10 of 26
WDR26
Tbio
Novelty:  0.04140166
Score:  0.779
Data Source:  STRINGDB
NBEAL1
Tbio
Novelty:  0.22337499
Score:  0.74
Data Source:  STRINGDB
ARMC8
Tbio
Novelty:  0.06820746
Score:  0.739
Data Source:  STRINGDB
SERTAD4
Tdark
Novelty:  0.70786986
Score:  0.705
Data Source:  STRINGDB
ZBTB44
Tdark
Family:  TF
Novelty:  0.75195191
Score:  0.687
Data Source:  STRINGDB
DHX40
Tdark
Family:  Enzyme
Novelty:  0.27906444
Score:  0.648
Data Source:  STRINGDB
RANBP9
Tbio
Novelty:  0.02182372
Score:  0.643
Data Source:  STRINGDB
PTPN4
Tchem
Family:  Enzyme
Novelty:  0.02977641
Score:  0.638
Data Source:  STRINGDB
PPIL2
Tbio
Family:  Enzyme
Novelty:  0.04860473
Score:  0.624
Data Source:  STRINGDB
MAEA
Tbio
Novelty:  0.00833813
Score:  0.6
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.57

PubMed score by year
PubTator Score  0.54

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer