Tbio BTBD9 BTB/POZ domain-containing protein 9

Protein Summary

Description

This locus encodes a BTB/POZ domain-containing protein. This domain is known to be involved in protein-protein interactions. Polymorphisms at this locus have been reported to be associated with susceptibility to Restless Legs Syndrome and may also be associated with Tourette Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011]

Uniprot Accession IDs

• Q96Q07
• Q494V9
• Q494W1
• Q96M00

Gene Name

• BTBD9

Ensembl ID

• ENST00000314100
• ENSP00000323408
• ENSG00000183826
• ENST00000419706
• ENSP00000415365
• ENST00000481247
• ENSP00000418751
• ENST00000649492
• ENSP00000497066

Symbol

• KIAA1880
• dJ322I12.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.92
protein domain	0.85
microRNA	0.84
transcription factor binding site profile	0.78
disease perturbation	0.74

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.59   (req: < 5)

Gene RIFs: 19   (req: <= 3)

Antibodies: 110   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.59   (req: >= 5)

Gene RIFs: 19   (req: > 3)

Antibodies: 110   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0