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Tdark
LENG8
Leukocyte receptor cluster member 8

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000326764
  • ENSP00000318374
  • ENSG00000167615
  • ENST00000610314
  • ENSP00000484494
  • ENSG00000274305
  • ENST00000611866
  • ENSP00000479293
  • ENSG00000276681
  • ENST00000616932
  • ENSP00000477813
  • ENST00000617180
  • ENSP00000480663
  • ENST00000617420
  • ENSP00000481040
  • ENSG00000276458
  • ENST00000621306
  • ENSP00000478337
  • ENST00000622672
  • ENSP00000478975

Symbol
  • KIAA1932
  • pp13842
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.82
cell line
0.72
histone modification site profile
0.71
cellular component
0.64
tissue sample
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.48   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 43   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.48   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 43   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (60)
PLCD4
Tbio
Family:  Enzyme
Novelty:  0.07014141
p_int:  0.999986262
p_ni:  0.000013738
Data Source:  BioPlex
PPP1CC
Tchem
Family:  Enzyme
Novelty:  0.00465946
p_int:  0.999984079
p_ni:  0.000015921
Data Source:  BioPlex
CSNK2B
Tbio
Family:  Kinase
Novelty:  0.00152367
p_int:  0.999972735
p_ni:  0.000027264
Score:  0.32
Data Source:  BioPlex,STRINGDB
PIP4K2A
Tbio
Family:  Kinase
Novelty:  0.01130885
p_int:  0.999800855
p_ni:  0.000199145
Data Source:  BioPlex
MPHOSPH6
Tbio
Family:  Enzyme
Novelty:  0.24387167
p_int:  0.999452519
p_ni:  0.000547481
Data Source:  BioPlex
PLEKHJ1
Tdark
Novelty:  1.44399298
p_int:  0.988523477
p_ni:  0.011476511
p_wrong:  1.1e-8
Data Source:  BioPlex
TACR3
Tchem
Family:  GPCR
Novelty:  0.00351352
p_int:  0.983694991
p_ni:  0.016305008
p_wrong:  1e-9
Data Source:  BioPlex
PROK2
Tbio
Novelty:  0.00512397
p_int:  0.9816401
p_ni:  0.018068935
p_wrong:  0.000290965
Data Source:  BioPlex
CCDC59
Tbio
Novelty:  0.05894885
p_int:  0.970133683
p_ni:  0.029866317
Data Source:  BioPlex
FGF12
Tbio
Novelty:  0.02094849
p_int:  0.963969404
p_ni:  0.036026349
p_wrong:  0.000004247
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
12
8
23
98.8
apolipoprotein A 1 measurement
2
4
4
96.8
self reported educational attainment
1
1
1
45.7
stem Cell Factor measurement
1
1
1
34.8
1
1
0
1.5
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
23
98.8
apolipoprotein A 1 measurement
4
96.8
self reported educational attainment
1
45.7
stem Cell Factor measurement
1
34.8
0
1.5
31.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2142195
232798
Rat
RGD:1306180
361506
Dog
leukocyte receptor cluster member 8
VGNC:42636
476385
Horse
leukocyte receptor cluster member 8
VGNC:19630
100050072
Cow
leukocyte receptor cluster member 8
VGNC:30839
526370
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
leukocyte receptor cluster member 8
Horse
leukocyte receptor cluster member 8
Cow
leukocyte receptor cluster member 8
Publication Statistics
PubMed Score 1.48
PubMed score by year
PubTator Score 0.12
PubTator score by year
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Related Publications
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PMID
Year
Title