COL21A1
Collagen alpha-1(XXI) chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.79 | ||
tissue sample | 0.59 | ||
protein domain | 0.58 | ||
histone modification site profile | 0.54 | ||
cellular component | 0.52 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Collagen biosynthesis and modifying enzymes | ||||
Reactome | Collagen chain trimerization | ||||
Reactome | Collagen formation | ||||
Reactome | Extracellular matrix organization | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Collagen biosynthesis and modifying enzymes | ||||
Collagen chain trimerization | ||||
Collagen formation | ||||
Extracellular matrix organization | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 3 | 4 | 93.1 | |||||
peak expiratory flow | 1 | 1 | 1 | 58.4 | |||||
forced expiratory volume | 1 | 1 | 1 | 56 | |||||
pulse pressure measurement | 2 | 2 | 2 | 42.2 | |||||
FEV/FEC ratio | 1 | 1 | 1 | 30.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 4 | 93.1 | |||||
peak expiratory flow | 1 | 58.4 | |||||
forced expiratory volume | 1 | 56 | |||||
pulse pressure measurement | 2 | 42.2 | |||||
FEV/FEC ratio | 1 | 30.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | collagen type XXI alpha 1 chain | VGNC:10696 | 462788 | |||||
Macaque | collagen type XXI alpha 1 chain | 712070 | ||||||
Dog | collagen type XXI alpha 1 chain | VGNC:39467 | 474945 | |||||
Horse | collagen type XXI alpha 1 chain | VGNC:16732 | 100056839 | |||||
Opossum | collagen type XXI alpha 1 chain | 100018467 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | collagen type XXI alpha 1 chain | |||||
Macaque | collagen type XXI alpha 1 chain | |||||
Dog | collagen type XXI alpha 1 chain | |||||
Horse | collagen type XXI alpha 1 chain | |||||
Opossum | collagen type XXI alpha 1 chain | |||||
PMID | Year | Title |
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