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Tchem
CAMK1G
Calcium/calmodulin-dependent protein kinase type 1G

Protein Summary
Description
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1 (By similarity). This gene encodes a protein similar to calcium/calmodulin dependent protein kinase, however, its exact function is not known. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000009105
  • ENSP00000009105
  • ENSG00000008118
  • ENST00000361322
  • ENSP00000354861

Symbol
  • CLICK3
  • VWS1
  • VWS1
  • CLICK3
  • CLICKIII
  • dJ272L16.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.94
protein domain
0.85
cell line
0.61
microRNA
0.57
cellular component
0.5


Related Tools
Dark Kinase Knowledgebase
Thumbnail image for Dark Kinase Knowledgebase
The Dark Kinase Knowledgebase is an an online compendium of knowledge and experimental results of understudied kinases.
ProKinO
Thumbnail image for ProKinO
The ProKinO is a protein kinase-specific ontology, which provides a controlled vocabulary of terms, their hierarchy, and relationships unifying sequence, structure, function, mutation and pathway information on kinases.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.72   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 282   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.72   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 282   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 3
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
1
0
1.3
1.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.3
1.2
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
calcium/calmodulin dependent protein kinase IG
VGNC:9976
469667
Macaque
calcium/calmodulin dependent protein kinase IG
717624
Mouse
MGI:2388073
215303
Rat
RGD:621800
171358
Dog
calcium/calmodulin dependent protein kinase IG
VGNC:38679
490273
Species
Name
OMA
EggNOG
Inparanoid
Chimp
calcium/calmodulin dependent protein kinase IG
Macaque
calcium/calmodulin dependent protein kinase IG
Mouse
Rat
Dog
calcium/calmodulin dependent protein kinase IG
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q96NX5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Pathways (4)
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
Aldosterone synthesis and secretion
KEGG
Oxytocin signaling pathway
KEGG
Calcium signaling pathway
KEGG
Glioma
Name
Explore in Pharos
Explore in Source
Aldosterone synthesis and secretion
Oxytocin signaling pathway
Calcium signaling pathway
Glioma
Gene Ontology Terms (7)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (89)
1 – 10 of 89
ZBTB44
Tdark
Family:  TF
Novelty:  0.75195191
p_int:  0.999997728
p_ni:  8.59e-7
p_wrong:  0.000001413
Score:  0.386
Data Source:  BioPlex,STRINGDB
CAMK1D
Tchem
Family:  Kinase
Novelty:  0.0274233
p_int:  0.999923361
p_ni:  0.00000293
p_wrong:  0.000073709
Score:  0.536
Data Source:  BioPlex,STRINGDB
RFWD3
Tbio
Family:  Enzyme
Novelty:  0.0859205
p_int:  0.980252169
p_ni:  0.013174764
p_wrong:  0.006573067
Score:  0.323
Data Source:  BioPlex,STRINGDB
CALM1
Tclin
Novelty:  0.00308267
Score:  0.894
Data Source:  STRINGDB
NOS3
Tchem
Family:  Enzyme
Novelty:  0.00012407
Score:  0.805
Data Source:  STRINGDB
CALML5
Tbio
Novelty:  0.03240679
Score:  0.789
Data Source:  STRINGDB
CALML4
Tdark
Novelty:  0.44764047
Score:  0.786
Data Source:  STRINGDB
JAM2
Tbio
Novelty:  0.02059056
Score:  0.754
Data Source:  STRINGDB
CALM3
Tclin
Novelty:  0.00461552
Score:  0.743
Data Source:  STRINGDB
CREB1
Tbio
Family:  TF
Novelty:  0.00018059
Score:  0.731
Data Source:  STRINGDB
Publication Statistics
PubMed Score  6.72

PubMed score by year
PubTator Score  7.51

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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