Protein Summary
May play a role in pre-mRNA splicing as component of the spliceosome (PubMed:25599396). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (By similarity).
- ENST00000361952
- ENSP00000354518
- ENSG00000198783
- CCDC16
- OMCG1
- CCDC16
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.93 | ||
tissue | 0.68 | ||
transcription factor binding site profile | 0.67 | ||
cell type or tissue | 0.65 | ||
virus perturbation | 0.64 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.98 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 100 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.98 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 100 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 17
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (118)
PPIE
Family: Enzyme
Novelty: 0.01586411
p_int: 0.999999969
p_ni: 1.2e-8
p_wrong: 1.9e-8
Score: 0.983
Data Source: BioPlex,STRINGDB
PPIL2
Family: Enzyme
Novelty: 0.04860473
p_int: 0.999997176
p_ni: 0.000002823
p_wrong: 1e-9
Score: 0.801
Data Source: BioPlex,STRINGDB
SNRPE
Novelty: 0.02033423
p_int: 0.999883976
p_ni: 0.000116017
p_wrong: 7e-9
Data Source: BioPlex
SNW1
Novelty: 0.01423797
p_int: 0.99985443
p_ni: 0.000143876
p_wrong: 0.000001693
Score: 0.729
Data Source: BioPlex,STRINGDB
APPL1
Novelty: 0.00973424
p_int: 0.998266313
p_ni: 0.001567216
p_wrong: 0.000166471
Score: 0.197
Data Source: BioPlex,STRINGDB
PRPF19
Novelty: 0.01616737
p_int: 0.946679724
p_ni: 0.000256518
p_wrong: 0.053063758
Score: 0.977
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (6)
Reactome (6)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | DNA Repair | ||||
Reactome | Dual incision in TC-NER | ||||
Reactome | Formation of TC-NER Pre-Incision Complex | ||||
Reactome | Gap-filling DNA repair synthesis and ligation in TC-NER | ||||
Reactome | Nucleotide Excision Repair | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
DNA Repair | ||||
Dual incision in TC-NER | ||||
Formation of TC-NER Pre-Incision Complex | ||||
Gap-filling DNA repair synthesis and ligation in TC-NER | ||||
Nucleotide Excision Repair | ||||
Viral Interactions (0)
Gene Ontology Terms (22)
Functions (2)
Components (5)
Processes (15)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations ()
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
QT interval | 2 | 1 | 0 | 1.2 | 57.8 | ||||
macrophage inflammatory protein 1b measurement | 1 | 1 | 1 | 48.5 | |||||
pulse pressure measurement | 1 | 1 | 1 | 45.7 | |||||
TPE interval measurement | 1 | 1 | 1 | 21.5 | |||||
self reported educational attainment | 1 | 1 | 1 | 7.7 | |||||
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
QT interval | 0 | 1.2 | 57.8 | ||||
macrophage inflammatory protein 1b measurement | 1 | 48.5 | |||||
pulse pressure measurement | 1 | 45.7 | |||||
TPE interval measurement | 1 | 21.5 | |||||
self reported educational attainment | 1 | 7.7 | |||||
Find similar targets by:
IDG Resources
Orthologs (12)
1 – 5 of 12
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | zinc finger protein 830 | VGNC:9808 | 454580 | |||||
Macaque | zinc finger protein 830 | 715130 | ||||||
Mouse | MGI:1914233 | 66983 | ||||||
Rat | RGD:1562573 | 497967 | ||||||
Dog | zinc finger protein 830 | VGNC:48828 | 480608 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | zinc finger protein 830 | |||||
Macaque | zinc finger protein 830 | |||||
Mouse | ||||||
Rat | ||||||
Dog | zinc finger protein 830 | |||||
Publication Statistics
PubMed Score 2.98
PubMed score by year
PubTator Score 0.60
PubTator score by year
Related Publications
Text Mined References (12)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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