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Tdark
ZNF641
Zinc finger protein 641

Protein Summary
Description
Transcriptional activator. Activates transcriptional activities of SRE and AP-1.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301042
  • ENSP00000301042
  • ENSG00000167528
  • ENST00000448928
  • ENSP00000394627
  • ENST00000544117
  • ENSP00000437832
  • ENST00000547026
  • ENSP00000449974
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.83
virus perturbation
0.83
protein domain
0.73
kinase perturbation
0.66
histone modification site profile
0.63


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.82   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.82   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
75.1
glomerular filtration rate
3
2
2
6
65.3
hematocrit
1
1
1
59.7
hemoglobin measurement
1
1
1
56.9
erythrocyte count
1
1
1
45
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
75.1
glomerular filtration rate
2
6
65.3
hematocrit
1
59.7
hemoglobin measurement
1
56.9
erythrocyte count
1
45
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 641
708246
Mouse
MGI:2442788
239652
Rat
RGD:1310412
300197
Dog
zinc finger protein 641
VGNC:48783
100687233
Horse
zinc finger protein 641
VGNC:25367
100051076
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 641
Mouse
Rat
Dog
zinc finger protein 641
Horse
zinc finger protein 641
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (8)
1 – 8 of 8
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.903
Data Source: STRINGDB
ZNF804A
Tbio
Novelty: 0.00751648
Score: 0.603
Data Source: STRINGDB
SLC45A4
Tdark
Family: Transporter
Novelty: 0.53986457
Score: 0.559
Data Source: STRINGDB
GTF2A1
Tchem
Novelty: 0.19577296
Score: 0.511
Data Source: STRINGDB
LSM14B
Tdark
Novelty: 0.31832554
Score: 0.496
Data Source: STRINGDB
NR2C2
Tchem
Family: NR
Novelty: 0.00392355
Score: 0.484
Data Source: STRINGDB
CPQ
Tbio
Family: Enzyme
Novelty: 0.01954288
Score: 0.418
Data Source: STRINGDB
PQLC2L
Tdark
Novelty: 82
Score: 0.41
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.82

PubMed score by year
PubTator Score  1.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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