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Tbio
PRELID3A
PRELI domain containing protein 3A

Protein Summary
Description
In vitro, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space. Phosphatidic acid import is required for cardiolipin (CL) synthesis in the mitochondrial inner membrane.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000336990
  • ENSP00000338988
  • ENSG00000141391
  • ENST00000440960
  • ENSP00000404700
  • ENST00000592149
  • ENSP00000466737

Symbol
  • C18orf43
  • SLMO1
  • SLMO1
  • C18orf43
  • HFL-EDDG1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.62   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 20   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.62   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 20   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (48)
1 – 10 of 48
TRIAP1
Tbio
Novelty:  0.00773097
p_int:  0.999974579
p_ni:  1e-9
p_wrong:  0.00002542
Score:  0.992
Data Source:  BioPlex,STRINGDB
AMN1
Tbio
Novelty:  0.02370739
p_int:  0.965255335
p_ni:  1.8e-8
p_wrong:  0.034744647
Data Source:  BioPlex
KXD1
Tdark
Novelty:  0.32146379
p_int:  0.908390234
p_ni:  0.091609766
p_wrong:  1e-9
Data Source:  BioPlex
UBE3A
Tbio
Family:  Enzyme
Novelty:  0.00149368
p_int:  0.849135728
p_ni:  0.059443763
p_wrong:  0.091420509
Data Source:  BioPlex
PRELID1
Tbio
Novelty:  0.05605197
Score:  0.933
Data Source:  STRINGDB
TP53
Tchem
Family:  TF
Novelty:  0.00001907
Score:  0.9
Data Source:  STRINGDB
KLHL14
Tbio
Novelty:  0.1214402
Score:  0.7
Data Source:  STRINGDB
SUSD6
Tbio
Novelty:  0.08836898
Score:  0.658
Data Source:  STRINGDB
MZT1
Tdark
Novelty:  0.06713659
Score:  0.545
Data Source:  STRINGDB
UCK2
Tbio
Family:  Kinase
Novelty:  0.02417595
Score:  0.545
Data Source:  STRINGDB
Pathways (6)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Reactome
TP53 Regulates Transcription of Cell Death Genes
Reactome
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
TP53 Regulates Transcription of Cell Death Genes
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HGNC
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2442865
225655
Rat
RGD:1582858
690253
Dog
PRELI domain containing 3A
VGNC:44957
490561
Horse
PRELI domain containing 3A
VGNC:21824
100050468
Cow
PRELI domain containing 3A
VGNC:33308
616292
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
PRELI domain containing 3A
Horse
PRELI domain containing 3A
Cow
PRELI domain containing 3A
Publication Statistics
PubMed Score 0.62
PubMed score by year
PubTator Score 1.00
PubTator score by year