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Tdark
ZNF681
Zinc finger protein 681

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000402377
  • ENSP00000384000
  • ENSG00000196172
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.9
tissue
0.61
protein domain
0.58
cell line
0.53
tissue sample
0.49


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.2   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.2   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96N22-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (11)
1 – 10 of 11
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.904
Data Source: STRINGDB
OR52N4
Tdark
Family: oGPCR
Novelty: 2.21267737
Score: 0.646
Data Source: STRINGDB
TIGD7
Tdark
Novelty: 0.38962555
Score: 0.627
Data Source: STRINGDB
TIGD6
Tdark
Novelty: 4.01176838
Score: 0.582
Data Source: STRINGDB
NKAPL
Tbio
Novelty: 0.24172313
Score: 0.559
Data Source: STRINGDB
PHKG2
Tchem
Family: Kinase
Novelty: 0.064884
Score: 0.475
Data Source: STRINGDB
ABCC12
Tbio
Family: Transporter
Novelty: 0.06927244
Score: 0.459
Data Source: STRINGDB
ERV3-1
Tbio
Novelty: 0.00916582
Score: 0.459
Data Source: STRINGDB
ABCA13
Tbio
Family: Transporter
Novelty: 0.03723754
Score: 0.442
Data Source: STRINGDB
SRCAP
Tbio
Family: Enzyme
Novelty: 0.02446238
Score: 0.438
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.20

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer