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Tbio
JAKMIP1
Janus kinase and microtubule-interacting protein 1

Protein Summary
Description
Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000282924
  • ENSP00000282924
  • ENSG00000152969
  • ENST00000409021
  • ENSP00000386711
  • ENST00000409371
  • ENSP00000387042
  • ENST00000409831
  • ENSP00000386925
  • ENST00000410077
  • ENSP00000386745

Symbol
  • GABABRBP
  • JAMIP1
  • MARLIN1
  • JAMIP1
  • MARLIN1
  • Gababrbp
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.97
cell type or tissue
0.68
tissue
0.63
phenotype
0.61
PubMedID
0.61


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.54   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 161   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.54   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
janus kinase and microtubule interacting protein 1
VGNC:621
471130
Macaque
janus kinase and microtubule interacting protein 1
722750
Mouse
MGI:1923321
76071
Rat
RGD:1562401
305434
Dog
janus kinase and microtubule interacting protein 1
VGNC:49832
488830
Species
Name
OMA
EggNOG
Inparanoid
Chimp
janus kinase and microtubule interacting protein 1
Macaque
janus kinase and microtubule interacting protein 1
Mouse
Rat
Dog
janus kinase and microtubule interacting protein 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96N16-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (33)
Items per page:
1 – 5 of 33
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Integrated Breast Cancer Pathway
WikiPathways
Integrated Breast Cancer Pathway
WikiPathways
Alzheimers Disease
WikiPathways
Allograft Rejection
WikiPathways
Hepatitis C and Hepatocellular Carcinoma
Name
Explore in Pharos
Explore in Source
Integrated Breast Cancer Pathway
Integrated Breast Cancer Pathway
Alzheimers Disease
Allograft Rejection
Hepatitis C and Hepatocellular Carcinoma
Gene Ontology Terms (17)
Items per page:
10
1 – 7 of 7
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Inferred from Direct Assay (IDA)
MGI
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (42)
1 – 10 of 42
DCLRE1C
Tbio
Novelty: 0.01064408
p_int: 0.999999994
p_wrong: 6e-9
Data Source: BioPlex
CHTF18
Tbio
Novelty: 0.02470494
p_int: 0.999999837
p_ni: 1.32e-7
p_wrong: 3.2e-8
Data Source: BioPlex
GABBR1
Tclin
Family: GPCR
Novelty: 0.00086493
Score: 0.797
Data Source: STRINGDB
GABBR2
Tclin
Family: GPCR
Novelty: 0.00739771
Score: 0.744
Data Source: STRINGDB
CAMK1D
Tchem
Family: Kinase
Novelty: 0.0274233
Score: 0.659
Data Source: STRINGDB
GPR155
Tbio
Novelty: 0.20783226
Score: 0.634
Data Source: STRINGDB
TYK2
Tclin
Family: Kinase
Novelty: 0.00237955
Score: 0.619
Data Source: STRINGDB
JAK1
Tclin
Family: Kinase
Novelty: 0.00093625
Score: 0.604
Data Source: STRINGDB
ZFYVE28
Tbio
Novelty: 0.52872767
Score: 0.582
Data Source: STRINGDB
PPP1R7
Tbio
Family: Enzyme
Novelty: 0.02088568
Score: 0.58
Data Source: STRINGDB
Publication Statistics
PubMed Score  12.54

PubMed score by year
PubTator Score  7.12

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer