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Tdark
FAM218A
Protein FAM218A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000513876
  • ENSP00000427428
  • ENSG00000250486

Symbol
  • C4orf39
  • C4orf39
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.9
cellular component
0.84
histone modification site profile
0.65
cell type or tissue
0.63
tissue sample
0.6


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.05   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 1   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.05   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 1   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.2
1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96MZ4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (12)
1 – 10 of 12
FAM192A
Tdark
Novelty:  0.46220707
p_int:  0.991826378
p_ni:  0.008173622
Data Source:  BioPlex
MTMR9
Tbio
Novelty:  0.09702778
p_int:  0.990588989
p_ni:  0.009411
p_wrong:  1e-8
Data Source:  BioPlex
NME2P1
Tdark
Family:  Kinase
p_int:  0.988007664
p_ni:  0.011991936
p_wrong:  4.01e-7
Data Source:  BioPlex
FAT3
Tbio
Novelty:  0.03661008
p_int:  0.983024533
p_ni:  0.016975467
Data Source:  BioPlex
PSMG4
Tdark
Novelty:  0.05339077
p_int:  0.951718099
p_ni:  0.048280525
p_wrong:  0.000001376
Data Source:  BioPlex
PSMG3
Tchem
Novelty:  0.01730294
p_int:  0.810174493
p_ni:  0.174159791
p_wrong:  0.015665715
Data Source:  BioPlex
GGPS1
Tchem
Family:  Enzyme
Novelty:  0.00292258
p_int:  0.804456781
p_ni:  0.195543201
p_wrong:  1.7e-8
Data Source:  BioPlex
TMEM192
Tbio
Novelty:  0.30699087
Score:  0.642
Data Source:  STRINGDB
TRIM60
Tdark
Novelty:  0.32106417
Score:  0.588
Data Source:  STRINGDB
PLA2G4B
Tchem
Family:  Enzyme
Novelty:  0.12279341
Score:  0.511
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.05

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer