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Tbio
CMTM3
CKLF-like MARVEL transmembrane domain-containing protein 3

Protein Summary
Description
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361909
  • ENSP00000354579
  • ENSG00000140931
  • ENST00000424011
  • ENSP00000400482
  • ENST00000562707
  • ENSP00000455758
  • ENST00000565922
  • ENSP00000456426
  • ENST00000567572
  • ENSP00000455851

Symbol
  • CKLFSF3
  • BNAS2
  • CKLFSF3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
kinase perturbation
0.81
PubMedID
0.8
transcription factor binding site profile
0.79
transcription factor
0.75


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.31   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 121   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.31   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 121   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (47)
CKLF
Tbio
Novelty:  0.01452927
Score:  0.91
Data Source:  STRINGDB
CMTM1
Tbio
Novelty:  0.07270259
Score:  0.905
Data Source:  STRINGDB
CMTM2
Tbio
Novelty:  0.07380731
Score:  0.905
Data Source:  STRINGDB
CMTM4
Tbio
Novelty:  0.09490151
Score:  0.905
Data Source:  STRINGDB
BLNK
Tbio
Novelty:  0.00351169
Score:  0.853
Data Source:  STRINGDB
CMTM8
Tbio
Novelty:  0.0953768
Score:  0.743
Data Source:  STRINGDB
CMTM7
Tbio
Novelty:  0.12799659
Score:  0.739
Data Source:  STRINGDB
VEZT
Tbio
Novelty:  0.06274137
Score:  0.708
Data Source:  STRINGDB
SLC25A11
Tbio
Family:  Transporter
Novelty:  0.06125899
Score:  0.666
Data Source:  STRINGDB
SYNCRIP
Tbio
Novelty:  0.01479381
Score:  0.66
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
CKLF like MARVEL transmembrane domain containing 3
VGNC:8970
740642
Macaque
CKLF like MARVEL transmembrane domain containing 3
695592
Mouse
MGI:2447162
68119
Rat
RGD:1308763
291813
Dog
CKLF like MARVEL transmembrane domain containing 3
VGNC:39381
100686160
Species
Name
OMA
EggNOG
Inparanoid
Chimp
CKLF like MARVEL transmembrane domain containing 3
Macaque
CKLF like MARVEL transmembrane domain containing 3
Mouse
Rat
Dog
CKLF like MARVEL transmembrane domain containing 3
Publication Statistics
PubMed Score 25.31
PubMed score by year
PubTator Score 13.50
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title