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Tdark
ZSWIM3
Zinc finger SWIM domain-containing protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000255152
  • ENSP00000255152
  • ENSG00000132801

Symbol
  • C20orf164
  • PPP1R174
  • C20orf164
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.82
transcription factor binding site profile
0.65
tissue
0.52
tissue sample
0.52
cell line
0.45


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.64   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.64   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (31)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
15
15
26
99.7
triglyceride measurement
14
12
24
3.3
99.4
sleep duration
4
3
4
90.1
apolipoprotein B measurement
2
2
2
86.8
mean reticulocyte volume
1
1
1
83.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
26
99.7
triglyceride measurement
24
3.3
99.4
sleep duration
4
90.1
apolipoprotein B measurement
2
86.8
mean reticulocyte volume
1
83.9
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger SWIM-type containing 3
VGNC:10067
469957
Mouse
MGI:1914788
67538
Rat
RGD:1309789
311630
Dog
zinc finger SWIM-type containing 3
VGNC:48856
485901
Horse
zinc finger SWIM-type containing 3
VGNC:25421
100056419
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger SWIM-type containing 3
Mouse
Rat
Dog
zinc finger SWIM-type containing 3
Horse
zinc finger SWIM-type containing 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96MP5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (19)
1 – 10 of 19
ZNF507
Tdark
Family:  TF
Novelty:  1.0899905
Score:  0.541
Data Source:  STRINGDB
C9orf40
Tdark
Novelty:  2.72763898
Score:  0.51
Data Source:  STRINGDB
TSPYL5
Tbio
Novelty:  0.07013974
Score:  0.499
Data Source:  STRINGDB
SNX21
Tdark
Novelty:  0.32916633
Score:  0.474
Data Source:  STRINGDB
RASGEF1C
Tdark
Novelty:  0.93266395
Score:  0.456
Data Source:  STRINGDB
ZMYM1
Tdark
Novelty:  0.3860445
Score:  0.451
Data Source:  STRINGDB
ZNF622
Tbio
Novelty:  0.26258288
Score:  0.448
Data Source:  STRINGDB
TRMT1L
Tdark
Novelty:  0.30029348
Score:  0.446
Data Source:  STRINGDB
WFDC3
Tdark
Novelty:  1.00375952
Score:  0.445
Data Source:  STRINGDB
ZNF23
Tbio
Family:  TF
Novelty:  0.33673708
Score:  0.442
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.64

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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